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Arabidopsis thaliana gene AT3G11280, encoding myb family transcription factor.
TABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHSSUMMARY
RefSeq annotates 2 representative transcripts (NM included in AceView variants .a and .b).AceView summaryExpression:According to AceView, this gene is expressed at high level, 2.6 times the average gene in this release. The sequence of this gene is defined by 87 GenBank accessions from 83 cDNA clones, some from aerial (seen 15 times), mixed floral buds, roots (9:1) (11), see description (10), roots (6), root (4), hormone treated callus (2), leaf (2) and 7 other tissues.Alternative mRNA variants and regulation:The gene contains 2 different gt-ag introns. Transcription produces 3 different mRNAs, 2 alternatively spliced variants and 1 unspliced form. There are 2 validated alternative polyadenylation sites (see the diagram). The mRNAs appear to differ alternative splicing or retention of one intron.Protein coding potential:The 2 spliced and the unspliced mRNAs putatively encode good proteins, altogether 3 different isoforms (2 complete, 1 COOH complete), some containing Myb, DNA-binding domain [Pfam].Function:There are 2 articles specifically referring to this gene in PubMed. Functionally, the gene has been proposed to participate in processes (regulation of transcription, response to salicylic acid stimulus). Proteins are expected to have molecular functions (transcription factor activity, DNA binding) and to localize in nucleus.Please see the Arabidopsis TAIR site TAIR:AT3G11280 for in depth functional annotation of this gene.Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12
Map on chromosome 3, links to other databases and other names   ?
Map:This gene AT3G11280 maps on chromosome 3. In AceView, it covers 1.63 kb, from 3534853 to 3533222 (NCBI 7_1, April 2007), on the reverse strand.Links to:manual annotations from TAIR:AT3G11280, the SNP view, gene overviews from Entrez Gene 820299, expression data from UniGene.Other names:The gene is also known as AT3G11280, MYB-LIKE PROTEIN or TF2, LOC820299. It has been described as myb family transcription factor.
Closest AceView homologs in other species   ?
The closest human genes, according to BlastP, are the AceView genes ZRF1 (e=10^-07,), PMPCB (e=2 10^-06,).The closest mouse gene, according to BlastP, is the AceView gene Dnajc2 (e=2 10^-07,).The closest C.elegans gene, according to BlastP, is the AceView/WormGene 3J914 (e=0.002,), which may contain interesting functional annotation
Complete gene on genome diagram:                (in true scale, with colored introns) Compact gene diagram
Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNA clones supporting each intron.Mouse over the ending of each transcript gives tissues from which the supporting cDNAs were extracted. Click on any transcript to open the specific mRNA page, to see the exact cDNA clone support and eventual SNPs and to get details on tissues, sequences, mRNA and protein annotations. Details on tissue of origin for each intron and exon is available from the intron and exons table. Good predicted proteins are in pink or blue, yellow proteins may be partial or unconvincing. Proteins supported by a single continuous GenBank accession lead to underlining the name/ending of the variant. Names not underlined result from cDNA concatenation in the coding region and should be experimentally checked.Caption



IP属地:上海1楼2011-05-29 18:53回复
    Sequences What is known about the gene and its neighbors on chromosome 3
    ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications          (see the Legend)
    Annotated mRNA diagrams Bibliography:               2 articles in PubMed
    To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function and related genes' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function and related genes' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation. To compare all variants, their summarized annotations, introns and exons, or to access any sequence, click the 'Alternative mRNAs features' tab. To see a specific mRNA variant diagram, sequence and annotation, click the variant name in the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'. If you know more about this gene, or found errors, please share your knowledge. Merci ! 


    IP属地:上海2楼2011-05-29 18:53
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      可以帮忙翻译一下么???


      IP属地:上海3楼2011-05-29 18:54
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