以下是关于山奈酚的外国文献整理,以下是分类明细
1—11:防癌、抗癌
1:宫颈癌
2:前列腺癌
4:大肠腺瘤
5:胰腺癌
6:儿童髓母细胞瘤
7:肺癌
8:胰腺癌
9:结肠癌
12、13、15、16、17:抗细菌、抗感染、抗炎症
14:抗病毒
18、19、25:动脉硬化,脑保护
20、21:糖尿病
22:有效的蛋白酶CK2的抑制剂,抗病毒,抗肿瘤,尤其是艾滋病和肿瘤癌症
23、24:自身免疫性疾病和器官移植排斥反应
26:抗过敏,预防变态反应
27、控制黏蛋白高分泌的气道炎症
28、镇痛
29、调节基因表达
参考文献整理(国外发表的关于山奈酚的论文)
【1】XUW,LIUJ,LIC,etal.Kaempferol-7-O-β-D-gluco-side(KG)isolatedfromSmilaxchinaL.rhizomeinducesG2/MphasearrestandapoptosisonHeLacellsinap53-independentmanner〔J〕.CancerLett,2008,264(2):229-240
【2】BANDYOPADHYAYS,ROMEROJR,CHATTOPADHYAYN.Kaempferolandquercetinstimulategranulocyte-macrophagecolo-ny-stimulatingfactorecretioninhumanprostatecancercells〔J〕.MolCellEndocrinol,2008,287(1/2):57-64.
【3】SHARMAV,JOSEPHC,GHOSHS,etal.Kaempferolinducesapoptosisinglioblastomacellsthroughoxidativestress〔J〕.MolCancerTher,2007,6(9):2544-2553.
【4】BOBEG,SANSBURYLB,ALBERTPS,etal.Dietaryfla-vonoidsandcolorectaladenomarecurrenceinthepolyppreventiontrial〔J〕.CancerEpidemiolBiomarkersPrev,2008,17(6):1344-1353.
【5】NOTHLINGSU,MURPHYSP,WILKENSLR,etal.Flavonolsandpancreaticcancerrisk:themultiethniccohortstudy〔J〕.AmJEpidemiol,2007,166(8):924-931.
【6】LABBED,PROVENCALM,LAMYS,etal.Theflavonolsquer-cetin,kaempferol,andmyricetininhibithepatocytegrowthfactor-inducedmedulloblastomacellmigration〔J〕.JNutr,2009,139(4):646-652.
【7】LEUNGHW,LINCJ,HOURMJ,etal.Kaempferolinducesapoptosisinhumanlungnon-smallcarcinomacellsaccompaniedbyaninductionofantioxidantenzymes〔J〕.FoodChemToxicol,2007,45(10):2005-2013.
【8】ZHANGY,CHENAY,LIM,etal.GinkgobilobaExtractKaempferolInhibitsCellProliferationandInducesApoptosisinPancreaticCancerCells〔J〕.JSurgRes,2008,148(1):17-23.
【9】YOSHIDAT,KONISHIM,HORINAKAM,etal.KaempferolsensitizescoloncancercellstoTRAIL-inducedapoptosis〔J〕.BiochemBiophysResCommun,2008,375(1):129-133.
【10】OFERM,WOLFFRAMS,KOGGELA,etal.Modulationofdrugtransportbyselectedflavonoids:InvolvementofP-gpandOCT?〔J〕.EurJPharmSci,2005,25(2/3):263-271.
【11】LIMTRAKULP,KHANTAMATO,PINTHAK.InhibitionofPglycoproteinfunctionandexpressionbykaempferolandquercetin〔J〕.JChemother,2005,17(1):86-95.
【12】XUHX,LEESF.Ativityofplantflavonoidsagainstantibiotic-resistantbacteria〔J〕.PhytotherRes,2001,15(1):39-43.
【13】MARTININD,KATEREREDR,ELOFFJN.Biologicalactivi-tyoffiveantibacterialflavonoidsfromCombretumerythrophyllum(Combretaceae)〔J〕.JEthnopharmacol,2004,93(2/3):207-212
【14】LIJ,HUANGH,ZHOUW,etal.Anti-hepatitisBVirusAc-tivitiesofGeraniumcarolinianumL.ExtractsandIdentificationoftheActiveComponents〔J〕.BiolPharmBull,2008,31(4):743-747.
【15】GARCIA-MEDIAVILLAV,CRESPOI,COLLADOPS,etal.Theanti-inflammatoryflavonesquercetinandkaempferolcauseinhibitionofinduciblenitricoxidesynthase,cyclooxygenase-2andreactiveC-protein,anddown-regulationofthenuclearfac-torkappaBpathwayinChangLivercells〔J〕.EurJPharmacol,2007,557(2/3):221-229.
【16】KOUY,INABAH,KATOT,etal.Inflammatory responsesof gingivalepithelialcellsstimulatedwithPorphyromonasgingivalisvesiclesareinhibitedbyhop-associatedpolyphenols〔J〕.JPeriodontol,2008,79(1):174-180.
【17】PANICOAM,CARDILEV,GARUFIF,etal.ProtectiveeffectofCapparisspinosaonchondrocytes〔J〕.LifeSci,2005,77(20):2479-2488.
【18】TUYC,LIANTW,YENJH,etal.AntiatherogenicEffectsofKaempferolandRhamnocitrin〔J〕.JAgricFoodChem,2007,55(24):9969-9976.
【19】CRESPOI,GARCIAMEDIAVILLAMV,GUTIERREZB,etal.Acomparisonoftheeffectsofkaempferolandquercetinoncyto-kine-inducedpro-inflammatorystatusofculturedhumanendo-thelialcells〔J〕.BrJNutr,2008,100(5):968-976.
【20】FANGXK,GAOJ,ZHUDN.Kaempferolandquercetinisola-tedfromEuonymusalatusimproveglucoseuptakeof3T3-L1cellswithoutadipogenesisactivity〔J〕.LifeSci,2008,82(11/12):615-622.
【21】DA SILVAWS,HARNEYJW,KIMBW,etal.Thesmallpolyphenolicmoleculekaempferolincreasescellularenergyex-penditureandthyroidhormoneactivation〔J〕.Diabetes,2007,56(3):767-776.
【22】LINXC,LIUXG,CHENXW,etal.InhibitoryEffectofKaempferolonProteinKinaseCK2invitroandinHL-60Cells〔J〕.ChinJBiochemMolBiol,2006,22(11):894-901.
【23】WANGH,ZHOUCL,LEIH,etal.Kaempferol:anewimmu-nosuppressantofcalcineurin〔J〕.IUBMBLife,2008,60(8):549-554.
【24】OKAMTOI,IWAKIK,KOYA-MIYATAS,etal.Thefla-vonoidkaempferolsuppressesthegraft-versus-hostreactionbyinhibitingtype1cytokineproductionandCD8+Tcellengraft-ment〔J〕.ClinImmunol,2002,103(2):132-144.
【25】ZHANGWZ,ZHOUX,ZHAOXZ.StudiesonkaempferolandQuercetinofFlavonolaglycone〔J〕.ChinJMisdiagn,2007,7(22):5219-5220.
【26】SHIMSY,CHOIJS,BYUNDS.KaempferolisolatedfromNe-lumbonuciferastamensnegativelyregulatesFcepsilonRIexpressioninhumanbasophilicKU812Fcells〔J〕.JMicrobiolBiotechnol,2009,19(2):155-160.
【27】KWONSH,NAMJI,KIMSH,etal.Kaempferolandquerce-tin,essentialingredientsinGinkgobilobaextract,inhibitinterleu-kin-1beta-inducedMUC5ACgeneexpressioninhumanairwayepithelialcells〔J〕.PhytotherRes,2009,23(12):1708-1712.
【28】DEMELOGO,MALVARDDOC,VANDERLINDEFA,etal.Antinociceptiveandanti-inflammatorykaempferolglycosidesfromSedumdendroideum〔J〕.JEthnopharmacol,2009,124(2):228-232.
【29】KANGBY,KIMS,LEEKH,etal.TranscriptionalprofilinginhumanHaCaTkeratinocytesinresponsetokaempferolandidenti-ficationofpotentialtranscriptionfactorsforregulatingdifferentialgeneexpression〔J〕.ExpMolMed,2008,40(2):208-219.