范 文 海，男，籍贯，山东鱼台，出生1972、4，
民族，汉，无党派，博士，专业，神经外科，主任医师
学 习 经 历：
1991.9-1996.7 内蒙古民族大学医学院临床医学系学习
1996．8月，内蒙古扎兰屯市医院外科
1999．3-2000.3哈尔滨医科大学第一医院进修脑外科
2000．9-2003.9吉林大学第一医院攻读神经外科硕士
2004-2009扎兰屯市中蒙医院建脑外科主任
2009.9-2012.7吉林大学第一医院攻读神经外科博士
文 章 课 题：
1.Wenhai Fan, Yi Hou, Fankai Meng, Xiaofei Wang, Yinan Luo, Pengfei GE. Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress. Acta Pharmacologica Sinica.2011,32(5):619-625.
2.Pengfei Ge,Liu Bin, Wenhai Fan, Shulei Li, Fuwei Yang, Yinan Luo, Ping Zhang. Aggregation patterns of proteasome in injured neurons induced by transient cerebral ischemia. Chemical Research in Chinese Universities. 2011,27(2):249-253.
3.G-M Wang, S-L Fu, P-F Ge, W-H Fan,G-M Li,F-K Meng,Y-N Luo.Use of a New Type of Trocar for the Surgical Treatment of Hydrocephalus: a Simple and Effective Technique. J Int Med Res 2011,39(3):766-771.
4. Wenhai Fan, Lihong Zhang, Zilong Zhang, Jingfu Guo,Aiming Ren.
Theoretical Study on Antitumor Activities of the Naphthoquinone Derivatives.(in press)
5.Lixiang Zhou,Xudong Guo,Mo Chen,Shuanglin Fu, Jinbing Zhou,Gang Ren,Zirong Yang, Wenhai Fan.Inhibition of δ‑opioid receptors induces brain glioma cell apoptosis through the mitochondrial and protein kinase C pathways. Oncology Letters 6:1351-57,2013.(通讯作者）
6.Ruijian Zhang,Ruijun Wang,Hong Chang,Fei Wu,Chuntao Liu,Dongfeng Deng,Wenhai Fan.Downregulation of Ezh2 expression by RNA interference induces cell cycle arrest in the G0/G1 phase and apoptosis in U87 human glioma cells.Oncology Reports 28:2278-84,2012.(通讯作者）
7.FAN Wen-Hai, ZHANG Li-Hong, ZHANG Zi-Long, GUO Jing-Fu, REN Ai-Min, GE Peng-Fei.Theoretical Study on Antitumor Activities of Naphthoquinone Derivatives .Chemical Journal Of Chinese Universities. 2013,34:1731-38.
8.Xiaohang Guo, Wenhai Fan, Xinchao Bian, Dihui Ma.Upregulation of the Kank1 gene-induced brain glioma apoptosis and blockade of the cell cycle in G0/G1 phase.Int J Oncol.2014 Mar;44(3):797-804.
9.Bo Tang, Wei Wu, Xiaowei Wei, Yang Li, Gang Ren and Wenhai Fan*. Activation of glioma cells generates immune tolerant NKT cells. J Biol Chem. 2014 Dec 12;289(50):34595-600.
参与国家自然科学基金面上项目（项目编号：81072071）--调控自噬对抑制蛋白酶体活性所致胶质瘤细胞死亡的影响（34万元），本人承担了课题的大部分实验工作。
民族，汉，无党派，博士，专业，神经外科，主任医师
学 习 经 历：
1991.9-1996.7 内蒙古民族大学医学院临床医学系学习
1996．8月，内蒙古扎兰屯市医院外科
1999．3-2000.3哈尔滨医科大学第一医院进修脑外科
2000．9-2003.9吉林大学第一医院攻读神经外科硕士
2004-2009扎兰屯市中蒙医院建脑外科主任
2009.9-2012.7吉林大学第一医院攻读神经外科博士
文 章 课 题：
1.Wenhai Fan, Yi Hou, Fankai Meng, Xiaofei Wang, Yinan Luo, Pengfei GE. Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress. Acta Pharmacologica Sinica.2011,32(5):619-625.
2.Pengfei Ge,Liu Bin, Wenhai Fan, Shulei Li, Fuwei Yang, Yinan Luo, Ping Zhang. Aggregation patterns of proteasome in injured neurons induced by transient cerebral ischemia. Chemical Research in Chinese Universities. 2011,27(2):249-253.
3.G-M Wang, S-L Fu, P-F Ge, W-H Fan,G-M Li,F-K Meng,Y-N Luo.Use of a New Type of Trocar for the Surgical Treatment of Hydrocephalus: a Simple and Effective Technique. J Int Med Res 2011,39(3):766-771.
4. Wenhai Fan, Lihong Zhang, Zilong Zhang, Jingfu Guo,Aiming Ren.
Theoretical Study on Antitumor Activities of the Naphthoquinone Derivatives.(in press)
5.Lixiang Zhou,Xudong Guo,Mo Chen,Shuanglin Fu, Jinbing Zhou,Gang Ren,Zirong Yang, Wenhai Fan.Inhibition of δ‑opioid receptors induces brain glioma cell apoptosis through the mitochondrial and protein kinase C pathways. Oncology Letters 6:1351-57,2013.(通讯作者）
6.Ruijian Zhang,Ruijun Wang,Hong Chang,Fei Wu,Chuntao Liu,Dongfeng Deng,Wenhai Fan.Downregulation of Ezh2 expression by RNA interference induces cell cycle arrest in the G0/G1 phase and apoptosis in U87 human glioma cells.Oncology Reports 28:2278-84,2012.(通讯作者）
7.FAN Wen-Hai, ZHANG Li-Hong, ZHANG Zi-Long, GUO Jing-Fu, REN Ai-Min, GE Peng-Fei.Theoretical Study on Antitumor Activities of Naphthoquinone Derivatives .Chemical Journal Of Chinese Universities. 2013,34:1731-38.
8.Xiaohang Guo, Wenhai Fan, Xinchao Bian, Dihui Ma.Upregulation of the Kank1 gene-induced brain glioma apoptosis and blockade of the cell cycle in G0/G1 phase.Int J Oncol.2014 Mar;44(3):797-804.
9.Bo Tang, Wei Wu, Xiaowei Wei, Yang Li, Gang Ren and Wenhai Fan*. Activation of glioma cells generates immune tolerant NKT cells. J Biol Chem. 2014 Dec 12;289(50):34595-600.
参与国家自然科学基金面上项目（项目编号：81072071）--调控自噬对抑制蛋白酶体活性所致胶质瘤细胞死亡的影响（34万元），本人承担了课题的大部分实验工作。
