语境：看起来好像在为什么事情担忧、不安。

Is something bothering you? You can talk to me.

You look like you've got something on your mind. Want to share?

You look worried. Everything okay?很简单明了的问法，worried /ˈwʌrid/ 担忧的，不安的。

You seem a bit down. Is everything alright?down在这里是形容词，表示sad or depressed，情绪低落的，伤心的。

You seem distracted. Are you okay?distracted /dɪˈstræktɪd/ 形容词，表示unable to pay attention because you are worried or thinking about something else，心里在思考担心某事，因为心事而分心，没办法专注于其他事。

You seem preoccupied. Is there anything I can do?preoccupied /priˈɒkjupaɪd/ 表示 thinking and worrying about something so that you do not pay attention to other things，心里在思考担心某事，注意力都被心事占用了，无法关注别的事情，和上一个句子意思差不多。